Pregnenolone

Pregnenolone is the master hormone precursor—the raw material your body uses to make DHEA, testosterone, progesterone, estrogen, and cortisol. It’s produced mainly in the adrenal glands and brain, and plays a critical role in stress resilience, cognitive function, mood, and overall hormone balance. Low pregnenolone is often seen with burnout, chronic stress, or low DHEA/testosterone—especially if the pituitary signals look fine but downstream hormones are low.

Unit

ng/dL

Health impacts

Mood · Libido